C8856

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C8856

Sigma-Aldrich

 

Captopril

meets USP testing specifications

Synonym:N-[(S)-3-Mercapto-2-methylpropionyl]-L-proline
CAS Number:62571-86-2
Linear Formula:C9H15NO3S
Molecular Weight:217.29
Beilstein Registry Number:477887
EC Number:263-607-1
MDL number:MFCD00168073
PubChem Substance ID:24893111

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Description

Biochem/physiol ActionsAngiotensin converting enzyme inhibitor. Inhibits the formation of angiotensin II, a bioactive peptide that stimulates angiogenesis and increases microvessel density.

Properties

mp104-108 °C(lit.)
suitabilitymeets USP testing specifications
Gene Informationhuman ... ACE(1636), ECE1(1889)
 rat ... Ace(24310)

Safety

Personal Protective Equipmentdust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard CodesXn
Risk Statements43-63
Safety Statements36/37
WGK Germany3
RTECSUY0550000

References

referenceGreene, A.S., and Amaral, S.L., Microvascular angiogenesis and the renin-angiotensin system. Curr. Hypertens. Rep. 4, 56-62, (2002)
 Hollenberg, N.K., Renal implications of angiotensin receptor blockers. Am. J. Hypertens. 14, 237S-241S, (2001)
 Gavras, H., and Brunner, H.R., Role of angiotensin and its inhibition in hypertension, ischemic heart disease, and heart failure. Curr. Hypertens. Rep. 37, 342-345, (2001)
MerckMerck 13,1780